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1

Glioblastoma: From Molecular Pathology to Targeted Treatment

Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2014

Language:

english

File:

PDF, 572 KB

english, 2014

2

The Impact of Sexual Imagery in Advertising: Comparing Hispanics’ and Non-Hispanics’ Attitudes and Responses Toward Print Ads

Kelsmark, Kevin Ann, Dion, Paul, Abratt, Russell, Mischel, Leann

Journal:

Journal of Promotion Management

Year:

2011

Language:

english

File:

PDF, 346 KB

english, 2011

3

Metabolic reprogramming in the pathogenesis of glioma: Update

Masui, Kenta, Onizuka, Hiromi, Cavenee, Webster K., Mischel, Paul S., Shibata, Noriyuki

Journal:

Year:

2019

Language:

english

File:

PDF, 1.28 MB

english, 2019

4

mTORC2 in the center of cancer metabolic reprogramming

Masui, Kenta, Cavenee, Webster K., Mischel, Paul S.

Journal:

Trends in Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

5

A restricted multinomial hybrid selection procedure

Vieira, Hélcio, Sanchez, Susan M., Sanchez, Paul J., Kienitz, Karl Heinz, Belderrain, Mischel Carmen Neyra

Journal:

ACM Transactions on Modeling and Computer Simulation

Year:

2014

Language:

english

File:

PDF, 395 KB

english, 2014

6

Single-cell analysis tools for drug discovery and development

Heath, James R., Ribas, Antoni, Mischel, Paul S.

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 965 KB

english, 2015

7

Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling

Liu, Feng, Mischel, Paul S., Cavenee, Webster K.

Journal:

npj Precision Oncology

Year:

2017

Language:

english

File:

PDF, 515 KB

english, 2017

8

Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response

Donoghue, Jacqueline, Kerr, Lauren, Alexander, Naomi, Greenall, Sameer, Longano, Anthony, Gottardo, Nicholas, Wang, Rong, Tabar, Viviane, Adams, Timothy, Mischel, Paul, Johns, Terrance

Journal:

Year:

2018

Language:

english

File:

PDF, 2.23 MB

english, 2018

9

Phase II Pilot Study of Bevacizumab in Combination with Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability

Albert Lai, Emese Filka, Bruce McGibbon, Phioanh Leia Nghiemphu, Carrie Graham, William H. Yong, Paul Mischel, Linda M. Liau, Marvin Bergsneider, Whitney Pope, Michael Selch, Tim Cloughesy

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 254 KB

english, 2008

10

RESTORATIVE PROCTOCOLECTOMY WITH ILEAL POUCH–ANAL ANASTOMOSIS IN 203 PATIENTS: THE AUCKLAND EXPERIENCE

Paul Neilly, Mischel E. Neill, Graham L. Hill

Journal:

ANZ Journal of Surgery

Year:

1999

Language:

english

File:

PDF, 42 KB

english, 1999

11

Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations

Franziska Niehr, Erika von Euw, Narsis Attar, Deliang Guo, Doug Matsunaga, Hooman Sazegar, Charles Ng, John A Glaspy, Juan A Recio, Roger S Lo, Paul S Mischel, Begonya Comin-Anduix, Antoni Ribas

Journal:

Journal of Translational Medicine

Year:

2011

Language:

english

File:

PDF, 2.62 MB

english, 2011

12

Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

Yohan Lee, Adrienne C Scheck, Timothy F Cloughesy, Albert Lai, Jun Dong, Haumith K Farooqi, Linda M Liau, Steve Horvath, Paul S Mischel, Stanley F Nelson

Journal:

BMC Medical Genomics

Year:

2008

Language:

english

File:

PDF, 1.45 MB

english, 2008

13

Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation

Eduard H. Panosyan, Dan R. Laks, Michael Masterman-Smith, Jack Mottahedeh, William H. Yong, Timothy F. Cloughesy, Jorge A. Lazareff, Paul S. Mischel, Theodore B. Moore, Harley I. Kornblum

Journal:

Pediatric Blood & Cancer

Year:

2010

Language:

english

File:

PDF, 238 KB

english, 2010

14

Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma

Dan R. Laks, Michael Masterman-Smith, Koppany Visnyei, Brigitte Angenieux, Nicholas M. Orozco, Ian Foran, William H. Yong, Harry V. Vinters, Linda M. Liau, Jorge A. Lazareff, Paul S. Mischel, Timothy

Journal:

Year:

2009

Language:

english

File:

PDF, 350 KB

english, 2009

15

A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM)

Teri N. Kreisl, Andrew B. Lassman, Paul S. Mischel, Neal Rosen, Howard I. Scher, Julie Teruya-Feldstein, David Shaffer, Eric Lis, Lauren E. Abrey

Journal:

Journal of Neuro-Oncology

Year:

2009

Language:

english

File:

PDF, 204 KB

english, 2009

16

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors

Qinghai Liu, David H. Nguyen, Qinghua Dong, Peter Shitaku, Kenneth Chung, On Ying Liu, Jonathan L. Tso, Jason Y. Liu, Veerauo Konkankit, Timothy F. Cloughesy, Paul S. Mischel, Timothy F. Lane, Linda M

Journal:

Journal of Neuro-Oncology

Year:

2009

Language:

english

File:

PDF, 846 KB

english, 2009

17

Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone

Melanie Kappadakunnel, Ascia Eskin, Jun Dong, Stanley F. Nelson, Paul S. Mischel, Linda M. Liau, Phioanh Ngheimphu, Albert Lai, Timothy F. Cloughesy, Jonathan Goldin, Whitney B. Pope

Journal:

Journal of Neuro-Oncology

Year:

2010

Language:

english

File:

PDF, 407 KB

english, 2010

18

Quantification of edema reduction using differential quantitative T2 (DQT2) relaxometry mapping in recurrent glioblastoma treated with bevacizumab

Benjamin M. Ellingson, Timothy F. Cloughesy, Albert Lai, Phioanh L. Nghiemphu, Shadi Lalezari, Taryar Zaw, Kourosh Motevalibashinaeini, Paul S. Mischel, Whitney B. Pope

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

19

Targeted Therapy for Malignant Glioma Patients: Lessons Learned and the Road Ahead

Tiffany T. Huang, Shawn M. Sarkaria, Timothy F. Cloughesy, Paul S. Mischel

Journal:

Neurotherapeutics

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

20

Targeted Molecular Therapy of GBM

Paul S. Mischel, Timothy F. Cloughesy

Journal:

Brain Pathology

Year:

2003

Language:

english

File:

PDF, 276 KB

english, 2003

21

New Roles for Galectins in Brain Tumors—From Prognostic Markers to Therapeutic Targets

Brianna N. Stillman, Paul S. Mischel, Linda G. Baum

Journal:

Brain Pathology

Year:

2005

Language:

english

File:

PDF, 192 KB

english, 2005

22

Genomic Landscape of Meningiomas

Yohan Lee, Jason Liu, Shilpa Patel, Timothy Cloughesy, Albert Lai, Haumith Farooqi, David Seligson, Jun Dong, Linda Liau, Donald Becker, Paul Mischel, Soheil Shams, Stanley Nelson

Journal:

Brain Pathology

Year:

2010

Language:

english

File:

PDF, 1.60 MB

english, 2010

23

Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line

Lu, Kan V, Jong, Kimberly A, Rajasekaran, Ayyappan K, Cloughesy, Timothy F, Mischel, Paul S

Journal:

Laboratory Investigation

Year:

2003

Language:

english

File:

PDF, 520 KB

english, 2003

24

DNA-microarray analysis of brain cancer: molecular classification for therapy

Mischel, Paul S., Cloughesy, Timothy F., Nelson, Stanley F.

Journal:

Nature Reviews Neuroscience

Year:

2004

Language:

english

File:

PDF, 336 KB

english, 2004

25

Identification of molecular subtypes of glioblastoma by gene expression profiling

Mischel, Paul S, Shai, Ruty, Shi, Tao, Horvath, Steve, Lu, Kan V, Choe, Gheeyoung, Seligson, David, Kremen, Thomas J, Palotie, Aarno, Liau, Linda M

Journal:

Year:

2003

Language:

english

File:

PDF, 474 KB

english, 2003

26

Gene expression profiling identifies molecular subtypes of gliomas

Shai, Ruty, Shi, Tao, Kremen, Thomas J, Horvath, Steve, Liau, Linda M, Cloughesy, Timothy F, Mischel, Paul S, Nelson, Stanley F

Journal:

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

27

p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition

Wang, Yinglin, Zhu, Shaojun, Cloughesy, Timothy F, Liau, Linda M, Mischel, Paul S

Journal:

Year:

2004

Language:

english

File:

PDF, 300 KB

english, 2004

28

Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients

Reardon, David A., Conrad, Charles A., Cloughesy, Timothy, Prados, Michael D., Friedman, Henry S., Aldape, Kenneth D., Mischel, Paul, Xia, Jane, DiLea, Clifford, Huang, Jerry, Mietlowski, William, Dug

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 416 KB

english, 2012

29

An Unbiased Screen Identifies DEP-1 Tumor Suppressor as a Phosphatase Controlling EGFR Endocytosis

Gabi Tarcic, Shlomit K. Boguslavsky, Jean Wakim, Tai Kiuchi, Angela Liu, Felicia Reinitz, David Nathanson, Takamune Takahashi, Paul S. Mischel, Tony Ng, Yosef Yarden

Journal:

Current Biology

Year:

2009

Language:

english

File:

PDF, 1.39 MB

english, 2009

30

Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks

Marc RJ Carlson, Bin Zhang, Zixing Fang, Paul S Mischel, Steve Horvath, Stanley F Nelson

Journal:

Year:

2006

Language:

english

File:

PDF, 1.64 MB

english, 2006

31

HOT Models in Flux: Mitochondrial Glucose Oxidation Fuels Glioblastoma Growth

Paul S. Mischel

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 111 KB

english, 2012

32

Robustness of gene expression profiling in glioma specimen samplings and derived cell lines

Ruty Mehrian Shai, Juergen K.V. Reichardt, Hsu Ya-Hsuan, Thomas J. Kremen, Linda M. Liau, Timothy F. Cloughesy, Paul S. Mischel, Stanley F. Nelson

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

33

Bilateral neuropathologic changes in a child with hemimegalencephaly

Reza Jahan, Paul S. Mischel, John G. Curran, Warwick J. Peacock, Donald W. Shields, Harry V. Vinters

Journal:

Pediatric Neurology

Year:

1997

Language:

english

File:

PDF, 2.69 MB

english, 1997

34

Nerve Growth Factor Signals via Preexisting TrkA Receptor Oligomers

Mischel, Paul S., Umbach, Joy A., Eskandari, Sepehr, Smith, Shane G., Gundersen, Cameron B., Zampighi, Guido A.

Journal:

Biophysical Journal

Year:

2002

Language:

english

File:

PDF, 417 KB

english, 2002

35

LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

Shackelford, David B., Abt, Evan, Gerken, Laurie, Vasquez, Debbie S., Seki, Atsuko, Leblanc, Mathias, Wei, Liu, Fishbein, Michael C., Czernin, Johannes, Mischel, Paul S., Shaw, Reuben J.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.12 MB

english, 2013

36

On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment

Eibinger, Gerald, Fauler, Günter, Bernhart, Eva, Frank, Sasa, Hammer, Astrid, Wintersperger, Andrea, Eder, Hans, Heinemann, Akos, Mischel, Paul S., Malle, Ernst, Sattler, Wolfgang

Journal:

Experimental Cell Research

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

37

Tumor cells with low proteasome subunit expression predict overall survival in head and neck cancer patients

Lagadec, Chann, Vlashi, Erina, Bhuta, Sunita, Lai, Chi, Mischel, Paul, Werner, Martin, Henke, Michael, Pajonk, Frank

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

38

Paul Mischel: All about Brains

Paul Mischel and Ruth Williams

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 550 KB

english, 2008

39

Arsenic reverses glioblastoma resistance to mTOR-targeted therapies

Iwanami, Akio, Cavenee, Webster K., Mischel, Paul S.

Journal:

Year:

2013

Language:

english

File:

PDF, 237 KB

english, 2013

40

mTORC2 dictates Warburg effect and drug resistance

Masui, Kenta, Cavenee, Webster K, Mischel, Paul S.

Journal:

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014

41

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death

Graham, Nicholas A, Tahmasian, Martik, Kohli, Bitika, Komisopoulou, Evangelia, Zhu, Maggie, Vivanco, Igor, Teitell, Michael A, Wu, Hong, Ribas, Antoni, Lo, Roger S, Mellinghoff, Ingo K, Mischel, Paul

Journal:

Molecular Systems Biology

Year:

2012

Language:

english

File:

PDF, 491 KB

english, 2012

42

Molecular Analysis of Glioblastoma: Pathway Profiling and Its Implications for Patient Therapy

Mischel, Paul S., Nelson, Stanley F., Cloughesy, Timothy F.

Journal:

Cancer Biology & Therapy

Year:

2003

Language:

english

File:

PDF, 420 KB

english, 2003

43

Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

Furnari, Frank B., Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.

Journal:

Nature Reviews Cancer

Year:

2015

Language:

english

File:

PDF, 504 KB

english, 2015

44

Recurrent Glioblastoma Multiforme: ADC Histogram Analysis Predicts Response to Bevacizumab Treatment 1

Pope, Whitney B., Kim, Hyun J., Huo, Jing, Alger, Jeffry, Brown, Matthew S., Gjertson, David, Sai, Victor, Young, Jonathan R., Tekchandani, Leena, Cloughesy, Timothy, Mischel, Paul S., Lai, Albert, Ng

Journal:

Year:

2009

Language:

english

File:

PDF, 459 KB

english, 2009

45

A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma

Read, Renee D., Fenton, Tim R., Gomez, German G., Wykosky, Jill, Vandenberg, Scott R., Babic, Ivan, Iwanami, Akio, Yang, Huijun, Cavenee, Webster K., Mischel, Paul S., Furnari, Frank B., Thomas, John

Journal:

Year:

2013

Language:

english

File:

PDF, 10.67 MB

english, 2013

46

Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance

Masui, Kenta, Tanaka, Kazuhiro, Ikegami, Shiro, Villa, Genaro R., Yang, Huijun, Yong, William H., Cloughesy, Timothy F., Yamagata, Kanato, Arai, Nobutaka, Cavenee, Webster K., Mischel, Paul S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

47

Lymphomatosis cerebri Presenting as a Rapidly Progressive Dementia: Clinical, Neuroimaging and Pathologic Findings

Bakshi, Rohit, Mazziotta, John C., Mischel, Paul S., Jahan, Reza, Seligson, David B., Vinters, Harry V.

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

1999

Language:

english

File:

PDF, 437 KB

english, 1999

48

Relationship between Gene Expression and Enhancement in Glioblastoma Multiforme: Exploratory DNA Microarray Analysis 1

Pope, Whitney B., Chen, Jenny H., Dong, Jun, Carlson, Marc R. J., Perlina, Alla, Cloughesy, Timothy F., Liau, Linda M., Mischel, Paul S., Nghiemphu, Phioanh, Lai, Albert, Nelson, Stanley F.

Journal:

Year:

2008

Language:

english

File:

PDF, 572 KB

english, 2008

49

Using molecular information to guide brain tumor therapy

Mischel, Paul S, Cloughesy, Timothy

Journal:

Nature Clinical Practice Neurology

Year:

2006

Language:

english

File:

PDF, 93 KB

english, 2006

50

Hamartin and Tuberin Interaction With the G2/M Cyclin-Dependent Kinase CDK1 and Its Regulatory Cyclins A and B

Catania, Michael G., Mischel, Paul S., Vinters, Harry V.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2001

File:

PDF, 2.18 MB

2001